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Türk e renen Yabanc lar n S zlük Kullanma Becerileri üzerine Bir Ara t rma
Murat ？zbay,Deniz Melanl？o？lu
Ana Dili E？itimi Dergisi , 2013,
Abstract: S zlük, yeni kelimelerin reniminde ba vurulan ana kaynakt r, denilebilir. Bu nedenle Türk enin yabanc lara retiminde de olduk a nemli bir materyaldir. Türk enin yabanc lara retimi üzerine pek ok al ma bulunmaktad r. Ancak s zlük kullan m üzerine olduk a s n rl say da al ma oldu u anla lmaktad r. Bu al man n amac , Türk e renen yabanc lar n, kelime hazinesinin geli iminde s zlük kullanma becerilerini tespit etmektir. Ara t rman n al ma grubunu 2011-2012 e itim retim y l nda Gazi T MER’de A2 kurunda bulunan renciler olu turmaktad r. Bu al ma, betimsel modelde tasarlanm t r. Ara t rmada nicel veri toplama tekniklerinden yararlan lm t r. Nicel veriler, “Yabanc rencilerin S zlük Kullanma Becerilerini Belirleme Anketi” ile toplanm ve verilerin analizinde SPSS 15.0 istatistik program kullan lm t r. Analiz sonucunda elde edilen bulgular do rultusunda Türk e renen yabanc lar i in seviyeler g z nüne al narak bir s zlük olu turulmas gerekti i eklinde birtak m neriler sunulmu tur.
Applications of Fluorescence in Situ Hybridization (FISH) for Detecting Genetic Changes in Hematological Malignancies  [PDF]
Deniz Ta？temir, Osman Demirhan, Emel Gürkan, Erdal Tun？, Nihal ？nand？kl？o？lu
Journal of Cancer Therapy (JCT) , 2011, DOI: 10.4236/jct.2011.22014
Abstract: Fluorescence in situ hybridization (FISH) has become an important tool both for defining initial chromosomal abnormalities within a disease process, and for monitoring response to therapy as well as minimal residual disease. We report the results of interphase FISH (iFISH) analysis of 92 patients. We have used five different FISH probes to detect common cytogenetic rearrangements associated with hematological malignancies. A total of 83 patients were screened for BCR/ABL gene rearrangements. Displayed iFISH patterns of BCR/ABL gene rearrangements in 37.3% of patients (31/83) ranged between 10% to 98%. In addition, while 3 patients and one patient with AML showed t(15; 17) (12.5%) and inv(16; 16) (8.3%) respectively, t(8; 21) was not found. Furthermore, secondary chromosomal aberrations (6.5% of all cases) were clearly non random in the present study. The diagnosis of BCR/ABL gene rearrangements are likely become an important tool for the monitoring of therapies in patients with CML. Atypical patterns also may have clinical prognostic implications. Further studies in larger groups of patients are needed in order to elucidate the role of AML1/ETO, PML/RARA, CBFB and p53, and to identify the specific chromosomal regions and interacting genes involved in this process.
Comparing The Databases Used in the Construction Cost Estimate in Turkey with Similar Databases in the World= Türkiye’de n aat Maliyeti Tahmininde Kullan lan Veri Tabanlar n n Dünyadaki Benzer rneklerleriyle Kar la t r lmas
Deniz Ay？e Yaz？c？o？lu
tasar？m + kuram , 2011,
Abstract: The aim of this research is to examine the structure of cost data bases which are used for building cost estimating in different design stages in Turkey and then to determine the problems of these cost data bases by comparing them with other cost data bases which are used in the world. Besides that, there will be advices to improve the cost data bases for more reliable cost estimating in Turkey. Bu al man n amac tasar m n tüm evreleri i in bina in aat maliyeti tahminine y nelik Türkiye’de kullan lan veri tabanlar n n yap lar n n tan mlanmas ve dünyadaki benzer rneklerle kar la t r larak zay f y nlerinin ortaya konulmas d r. Ayr ca Türkiye’deki bu veri tabanlar n n, daha güvenilir maliyet tahminlerinin yap lmas na imkan verecek bi imde iyile tirilmesine y nelik e itli nerilerde bulunulmas d r.
p53, bcl-2, and nm23 Expressions in Serous Ovarian Tumors: Correlation with the Clinical and Histopathological Parameters
Deniz ARIK,Sezer KULA？O？LU
Türk Patoloji Dergisi , 2011,
Abstract: Objective: We studied p53, bcl-2, and nm23 expressions in serous benign, borderline and malignant tumors of the ovary. Our aim was to determine the association between these expressions and some clinical (patient age, tumor dimension, omenthal involvement, the presence of malignant cells in peritoneal fluid) and histopathological (grade, number of mitosis, nuclear pleomorphism, structural pattern) parameters in malignant serous tumors.Material and Method: A total of 71 tumors including 29 benign, 14 borderline, and 28 malignant ovarian serous tumors were included in the study. p53, bcl-2, and nm23 immunohistochemical staining was performed on the paraffin blocks. The results were scored as (+), (++) and (+++) according to the extent of staining.Results: There was no staining for p53 in benign or borderline tumors. p53 was positive in 42.9% of malignant tumors. nm23 expression was revealed as 44.8%, 64.3% and 67.9% in benign, borderline and malignant tumors, respectively. Bcl-2 was positive in only 17.2% of benign, 35.7% of borderline and 25% of malignant tumors.Conclusion: The p53 positivity detected only in serous carcinomas shows its role in carcinogenesis. p53 was expressed at a significantly higher rate in advanced stage carcinomas (p=0.031). nm23 expression in benign, borderline and malignant tumors was not significantly different. nm23 positivity was higher in advanced stage carcinomas (p=0.032). This suggest that nm23 acts like an oncogene in ovarian carcinomas. There was no significant difference between the groups in terms of bcl-2 expression.
Mode-coupling points to functionally important residues in Myosin II
Onur Varol,Deniz Yuret,Burak Erman,Alkan Kabak？？o？lu
Quantitative Biology , 2013,
Abstract: Relevance of mode coupling to energy/information transfer during protein function, particularly in the context of allosteric interactions is widely accepted. However, existing evidence in favor of this hypothesis comes essentially from model systems. We here report a novel formal analysis of the near-native dynamics of myosin II, which allows us to explore the impact of the interaction between possibly non-Gaussian vibrational modes on fluctutational dynamics. We show that, an information-theoretic measure based on mode coupling {\it alone} yields a ranking of residues with a statistically significant bias favoring the functionally critical locations identified by experiments on myosin II.
The Moderating Role of General Self-Efficacy In The Relationship Between Perceptions of Safety Climate and Job Performance: A Study On Helicopter Mechanic and Avionics Technicians
Deniz Dirik,？nan Ery？lmaz,？ener Odaba？o？lu
- , 2019,
Abstract: The history of aviation brims with blood, thus the concept of safety is a matter of critical value for aviation industry. Perceptions of safety climate refer to employees’ view of how their organization handles safety-related processes. This study addresses the relationship between helicopter mechanic and avionics technicians’ perceptions of safety climate and facets of job performance, as the former provide a significant portion of the labor requirement in military aviation. The study also problematizes the role of self-efficacy perceptions in the aforementioned relationship. To that end, data was collected on a sample of 195 military aviation employees working in Ankara, Malatya and ？zmir through survey method. The recruited data was analyzed through IBM SPSS and Amos statistical analysis software. According to the findings of the study, there are significantly positive correlations between safety climate perceptions and job performance subscales. Self-efficacy has a moderating role in the relationship between perceptions of safety climate and task performance. However, the relationship between perceptions of safety climate and contextual performance is not moderated by self-efficacy
MERCHANDISE COST WITHIN FINANCIAL REPORTING STANDARD FOR LARGE AND MEDIUM-SIZED ENTITIES (FRS FOR LMES) AND TAX PROCEDURE LAW (TPL)
Günay Deniz Dursun,Kadir Dabba？o？lu
- , 2018,
Abstract: Inventory cost is calculated by non-public interest entities in accordance with two different regulations carried into effect by Tax Procedure Law and Financial Reporting Standards for large and medium-sized entities. Add to this, Financial Reporting Standards for large and medium-sized entities have alternative practices based on maturity. Therefore, different inventory cost and different accounting practice are both in question. The study examines and clarifies these differences with a critical approach. The study is supported with sample solutions and based on written printed sources relating to the topic. Results of sample solutions indicates that diversifying accounting practices depending on maturity conflict with qualified financial information. Because, ignoring interest and non-use of amortized cost method on purchase transaction with short term maturity are both at odds with basic rules of accounting such as accrual basis, matching principle, substance over form
GRANULOCYTE COLONY STIMULATING FACTOR AMELIORATES RADIATION-INDUCED MORPHOLOGICAL DESTRUCTION OF INTESTINAL MUCOSA IN RATS
Beste M. Atasoy,Mine Güng？r-Güllüo？lu,Ufuk Abac？o？lu,Mustafa Deniz
Marmara Medical Journal , 2008,
Abstract: Objective: We aimed to evaluate whether prophylactic administration of granulocyte colony-stimulating factor (G-CSF) has a protective effect on the morphology of irradiated intestinal mucosa.Methods: Twenty-three animals were divided into 4 groups: saline-treated control and G-CSF-injected control groups, irradiated group with saline injection and irradiated and G-CSF administered group. G-CSF (100μg/kg/day) was given subcutaneously for four consecutive days. Twelve hours after the fourth injection, under anaesthesia a single pelvic dose of 14 Gy ionising radiation was given to irradiated groups, while the control groups were not irradiated. On the fourth day of irradiation or sham-radiation, rats were sacrificed and terminal ileum and rectum samples were removed for histological assessment of mucosal injury.Results: Terminal ileum samples from both G-CSF treated and saline-treated control groups revealed minimum scores. In the saline-treated IR group, the score was significantly elevated as compared to either control groups. However, G-CSF administration preceding the irradiation reduced the severity of mucosal damage. On the other hand, the increased scores in the rectum samples of irradiated rats treated with either saline or G-CSF were not different from each other.Conclusion: Prophylactic administration of G-CSF might reduce ionising radiation-induced mucosal destruction of the terminal ileum, but not the rectum.
A study on the morphometric characteristics of Astacus leptodactylus inhabiting the Thrace region of Turkey Une étude des caractéristiques morphométriques d’Astacus leptodactylus dans la région de la Thrace en Turquie
Deniz (B？k) T.,Harl？o？lu M.M.,Deval M.C.
Knowledge and Management of Aquatic Ecosystems , 2010, DOI: 10.1051/kmae/2010021
Abstract: This study was carried out to determine some morphological characteristics, and the length-length and length-weight relationships of freshwater crayfish (A. leptodactylus Eschscholtz 1823) in the area of Tekirda , in the Thrace region of Turkey. The total length and wet weight for all individuals ranged from 33 to 156 mm and 0.64 to 96.42 g, respectively. Although the average length of both sexes was nearly the same, the average weight of male crayfish was higher than that of females. The total length-wet weight relationships for males, females and combined sexes of wet weight were found to be: WW = 7.106TL3.293, WW = 2.105TL3.022 and WW = 9.106TL3.224, respectively. Isometric growth for female crayfish and positive allometric growth for male crayfish were observed in all populations. The carapace length, carapace width, and chela length and width increased allometrically with total length (TL) in both sexes. In conclusion, the morphometric relations in A. leptodactylus observed in the present study could provide information for future studies and management plans. Cette étude a été conduite pour déterminer quelques caractéristiques morphologiques, les relations longueur-longueur et longueur-poids de l’écrevisse d’eau douce (A. leptodactylus Eschscholtz 1823) dans la zone de Tekirda , dans la région Thrace de Turquie. Les longueurs totales et les poids frais de tous les individus vont de 33 à 156 mm et de 0,64 à 96,42 g respectivement. Bien que les longueurs moyennes des deux sexes soient très proches, le poids moyen des écrevisses males est supérieur à celui des femelles. La relation longueur totale (LT)-poids frais pour les males, femelles et sexes combinés, sont : WW = 7,106TL3,293, WW = 2,105TL3,022 et WW = 9,106TL3,224 respectivement. Une croissance isométrique pour les écrevisses femelles et allométrique positive pour les males a été observée dans toutes les populations. Les longueurs et largeurs de carapace et de pince croissent allométriquement avec la longueur totale dans les deux sexes. En conclusion, les relations morphométriques observées chez A. leptodactylus dans cette étude peuvent apporter des informations pour des études ultérieures et les plans de gestion.
Cardiac Allograft Vasculopathy and Coronary Artery Disease Development with Orthotopic Heart Transplantation
Deniz ？evirme,？lker Matarac？,O？uz Konuko？lu,Kaan K？rali
Ko？uyolu Kalp Dergisi , 2012,
Abstract: Cardiac allograft vasculopathy is an accelerated form coronary artery disease that characterized by development of fibrous intimal hyperplasia of all coronary artery. This is a major factor determining long-term survival in heart transplantation. Three (4%) patients were developed coronary artery disease and allograft vasculopathy from orthotopik heart transplantation in 62 patients at our clinic in late follow-up. There were two of the male, one female patients and age 22, 24 and 39, respectively. Because of development in young patients multivessel disease were performed invasive procedures. Women patient was died after diagnosed one year. Two patients continued medical follow-up. Allograft vasculopathy is very diffuse pathology that invasive procedures success is limited in the treatment.
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